PCOS and Weight Loss Medications

This article only provides general information and not substitute speaking to a medical professional.

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PCOS is a common endocrine disorder in females of reproductive condition, affecting 8-20% of the population. It’s a collection of symptoms (hence syndrome) driven by a hormone disturbance - typically two key hormones: androgens and insulin.

 

75% of women with PCOS also suffer from insulin resistance. This is when your cells found in muscles, fat and liver become less responsive to the action of insulin, a hormone made by the pancreas to regulate your blood sugars. This can result in higher levels of androgens (male sex hormones) in the body, which contribute to symptoms of PCOS, impact weight management and also lead to irregular cycles.

 

When it comes to weight loss medications, there haven’t been any clinical trials that have shown changes to one’s menstrual cycle or PCOS. Changes in your menstrual cycle may be related to the better management of your blood sugars and insulin levels.

 

In general, weight loss medications can affect blood sugar levels by increasing insulin secretion and inhibiting your glucagon release. Therefore, the medication doesn’t directly impact the menstrual cycle, however does affect blood sugar levels, helping to better regulate your hormones.

 

Some patient’s may find that with weight loss, periods become lighter and more regular which is usually a positive thing. We recommend that you track your menstrual cycle closely. If you have any concerns, please let our medical support team know here.